Saudi giants Al-Nassr have been strongly linked with the midfielder as they plan to link him up with Cristiano Ronaldo.
The Belgian is set to enter the final year of his contract next summer, with City facing the prospect of losing him for free in 2025.
According to TeamTalk, the Treble winners are instead open to selling De Bruyne.
Al-Nassr are understood to be leading the race to sign the 32-year-old and plan to make him one of the world’s highest-paid players.
De Bruyne has already been sounded out by the Saudi Pro League side over a potential move.
The report adds that City value De Bruyne at £60million and would look to bring in a long-term replacement if he is sold.
Pep Guardiola has been without his star playmaker since August after De Bruyne hobbled off against Burnley in their Premier League opener.
He has since missed 19 matches with the hamstring injury and it remains unknown when he will return to action.
His fitness woes have not put off Al-Nassr, though, who currently sit second in the Saudi Pro League.
